Pdgfratm1.1(cre/ERT2)Trdo
Targeted Allele Detail
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Symbol: |
Pdgfratm1.1(cre/ERT2)Trdo |
Name: |
platelet derived growth factor receptor, alpha polypeptide; targeted mutation 1.1, Thomas A Rando |
MGI ID: |
MGI:6377446 |
Synonyms: |
PDGFRalphaCreER |
Gene: |
Pdgfra Location: Chr5:75312953-75358876 bp, + strand Genetic Position: Chr5, 39.55 cM
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Alliance: |
Pdgfratm1.1(cre/ERT2)Trdo page
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Germline Transmission: |
Earliest citation of germline transmission:
J:280557
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Pdgfratm1.1(cre/ERT2)Trdo expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pdgfra (MGI:97530) |
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Mutation details: A targeting vector was designed to place a FRT-flanked neo cassete in intron 3 and CreERT2 minigene inserted after ATG start codon in exon 4 of the mouse PDGFRa locus. The neo marker was subsequently removed by crossing Flp deleter mouse.
(J:280557)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pdgfra
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pdgfra Mutation: |
85 strains or lines available
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Original: |
J:280557 Wosczyna MN, et al., Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle. Cell Rep. 2019 May 14;27(7):2029-2035.e5 |
All: |
1 reference(s) |
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