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Endonuclease-mediated Allele Detail
Symbol: Ube2q2lem1(IMPC)J
Name: ubiquitin conjugating enzyme E2 Q2 like; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6376261
Gene: Ube2q2l  Location: Chr6:136377315-136392567 bp, - strand  Genetic Position: Chr6, 66.59 cM
Alliance: Ube2q2lem1(IMPC)J page
IMPC: Ube2q2l gene page
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACACCATAGCAACTGCACAA and GATGGATTCTCCATGCTAAA, which resulted in a 1677 bp deletion beginning at Chromosome 6 position 136,400,277 bp and ending after 136,401,953 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001369384 (exon 2) and 107 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to generate a null allele. (J:188991)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ube2q2l Mutation:  18 strains or lines available
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
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