Dicer1^tm1Uky
Targeted Allele Detail

Summary

• Symbol: Dicer1^tm1Uky
• Name: dicer 1, ribonuclease type III; targeted mutation 1, University of Kentucky
• MGI ID: MGI:6370172
• Synonyms: Dicer^fl
• Gene: Dicer1 Location: Chr12:104654001-104718211 bp, - strand Genetic Position: Chr12, 54.83 cM, cytoband E-F1
• Alliance: Dicer1^tm1Uky page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279913
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 23 and 24, which encode the RNAse III domain, were floxed. (J:279913)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dicer1 Mutation: 96 strains or lines available

References

• Original: J:279913 Vechetti IJ Jr, et al., Life-long reduction in myomiR expression does not adversely affect skeletal muscle morphology. Sci Rep. 2019 Apr 2;9(1):5483
• All: 1 reference(s)