Mpeg1^tm1.1Pib
Targeted Allele Detail

Summary

• Symbol: Mpeg1^tm1.1Pib
• Name: macrophage expressed gene 1; targeted mutation 1.1, Phillip I Bird
• MGI ID: MGI:6368993
• Gene: Mpeg1 Location: Chr19:12438143-12442649 bp, + strand Genetic Position: Chr19, 8.72 cM
• Alliance: Mpeg1^tm1.1Pib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:341384
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination deleted of part of intron A and part of exon 2, removing the entire coding sequence and neomycin selectable marker. It leaves the promoter, part of 5'UTR and 3'UTR intact. (J:341384)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mpeg1 Mutation: 54 strains or lines available

References

• Original: J:341384 Ebrahimnezhaddarzi S, et al., Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation. Immunol Cell Biol. 2022 Aug;100(7):529-546
• All: 1 reference(s)