Galnt2^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Galnt2^tm1.1Mrl
• Name: polypeptide N-acetylgalactosaminyltransferase 2; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:6368824
• Gene: Galnt2 Location: Chr8:124958133-125072461 bp, + strand Genetic Position: Chr8, 72.52 cM, cytoband E2
• Alliance: Galnt2^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251899
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 4 to 6 were floxed. Flp-mediated recombination removed the selection cassette. (J:251899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Galnt2 Mutation: 38 strains or lines available

References

• Original: J:251899 Khetarpal SA, et al., Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents. Cell Metab. 2016 Aug 9;24(2):234-45
• All: 1 reference(s)