Erp44^tm1Kmik
Targeted Allele Detail

Summary

• Symbol: Erp44^tm1Kmik
• Name: endoplasmic reticulum protein 44; targeted mutation 1, Katsuhiko Mikoshiba
• MGI ID: MGI:6367640
• Synonyms: ERp44^-
• Gene: Erp44 Location: Chr4:48193323-48279558 bp, - strand Genetic Position: Chr4, 26.09 cM
• Alliance: Erp44^tm1Kmik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279802
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced by a neomycin-resistance expression cassette. Northern blot analysis on RNA derived from liver, brain, kidney and stomach showed that no detectable trasncript is expressed from this allele, compared to controls. (J:279802)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Erp44 Mutation: 45 strains or lines available

References

• Original: J:279802 Hisatsune C, et al., ERp44 Exerts Redox-Dependent Control of Blood Pressure at the ER. Mol Cell. 2015 Jun 18;58(6):1015-27
• All: 1 reference(s)