Ppp1r3gtm1Nju
Targeted Allele Detail
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Symbol: |
Ppp1r3gtm1Nju |
Name: |
protein phosphatase 1, regulatory subunit 3G; targeted mutation 1, Model Animal Research Center of Nanjing University |
MGI ID: |
MGI:6367634 |
Synonyms: |
PP1R3G- |
Gene: |
Ppp1r3g Location: Chr13:36142822-36154371 bp, + strand Genetic Position: Chr13, 14.44 cM
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Alliance: |
Ppp1r3gtm1Nju page
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Germline Transmission: |
Earliest citation of germline transmission:
J:249135
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Part of exon 2 was replaced by a PGK-neomycin cassette. Immunoblot analysis confirmed the complete absence of protein expression in the brain of homozygous mutant mice. No protein expression was detected in the liver of homozygous mutant mice upon fasting.
(J:249135)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ppp1r3g Mutation: |
11 strains or lines available
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Original: |
J:249135 Zhang Y, et al., Ablation of PPP1R3G reduces glycogen deposition and mitigates high-fat diet induced obesity. Mol Cell Endocrinol. 2017 Jan 5;439:133-140 |
All: |
1 reference(s) |
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