Klhl6^tm1Crey
Targeted Allele Detail

Summary

• Symbol: Klhl6^tm1Crey
• Name: kelch-like 6; targeted mutation 1, Claude-Agnes Reynaud
• MGI ID: MGI:6364886
• Gene: Klhl6 Location: Chr16:19765242-19801766 bp, - strand Genetic Position: Chr16, 12.32 cM
• Alliance: Klhl6^tm1Crey page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250892
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP-flanked neomycin selection cassette replaced exon 1. (J:250892)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klhl6 Mutation: 48 strains or lines available

References

• Original: J:250892 Bertocci B, et al., Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation. J Immunol. 2017 Oct 1;199(7):2408-2420
• All: 1 reference(s)