Ubl3^tm1Seto
Targeted Allele Detail

Summary

• Symbol: Ubl3^tm1Seto
• Name: ubiquitin-like 3; targeted mutation 1, Mitsutoshi Setou
• MGI ID: MGI:6363682
• Gene: Ubl3 Location: Chr5:148441445-148489599 bp, - strand Genetic Position: Chr5, 88.66 cM, cytoband G2-3
• Alliance: Ubl3^tm1Seto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268354
• Parent Cell Line: CCE916 (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 of mouse Ubl3 gene which contain an initiation codon was replaced with a neomycin selection cassette. The absence of protein expression was confirmed by western blot analysis on tissue extracts from homozygous mice. It is a null allele. (J:268354)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubl3 Mutation: 74 strains or lines available

References

• Original: J:268354 Ageta H, et al., UBL3 modification influences protein sorting to small extracellular vesicles. Nat Commun. 2018 Sep 26;9(1):3936
• All: 1 reference(s)