Tg(Vil1-cre)#Gum
Transgene Detail

Summary

• Symbol: Tg(Vil1-cre)#Gum
• Name: transgene insertion, Deborah L Gumucio
• MGI ID: MGI:6363341
• Synonyms: Vil1-cre, Vil-Cre, villin-Cre
• Transgene: Tg(Vil1-cre)#Gum Location: unknown Genetic Position: ChrUN, Syntenic
• Alliance: Tg(Vil1-cre)#Gum page

Transgene origin

• Strain of Origin: C57BL/6J x SJL/J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Vil1-cre)#Gum expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vil1 (MGI:98930)

• Mutation details: A transgenic construct containing the coding domain of Cre recombinase, driven by a 12.4 kb fragment of the mouse villin 1 gene, and a metallothionein polyadenylation site sequence was injected into the pronuclei of fertilized C57BL/6J x SJL/J mouse eggs. Seven lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:78815)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vil1 (mouse) Summary of all recombinase alleles driven by Vil1. Comparative matrix view of recombinase activities Alliance mouse Vil1 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Vil1-cre)#Gum

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78815 Madison BB, et al., cis Elements of the Villin Gene Control Expression in Restricted Domains of the Vertical (Crypt) and Horizontal (Duodenum, Cecum) Axes of the Intestine. J Biol Chem. 2002 Sep 6;277(36):33275-83
• All: 6 reference(s)