Glipr2^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Glipr2^em1(IMPC)J
• Name: GLI pathogenesis-related 2; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6362952
• Gene: Glipr2 Location: Chr4:43957702-43979118 bp, + strand Genetic Position: Chr4, 23.07 cM, cytoband B1
• Alliance: Glipr2^em1(IMPC)J page
• IMPC: Glipr2 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACATCCCTTCAACCACCCAG and AGAAGTACAAGTCAGAGGCG, which resulted in a 659 bp deletion beginning at Chromosome 4 position 43,968,272 bp and ending after 43,968,930 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000179593 (exon 3) and 555 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 41 and early truncation 5 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Glipr2 Mutation: 37 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 2 reference(s)