Scml1^tm1.1Atot
Targeted Allele Detail

Summary

• Symbol: Scml1^tm1.1Atot
• Name: Scm polycomb group protein like 1; targeted mutation 1.1, Attila Toth
• MGI ID: MGI:6362615
• Synonyms: Scml1^restored
• Gene: Scml1 Location: ChrX:160598170-160608319 bp, - strand Genetic Position: ChrX, 74.15 cM
• Alliance: Scml1^tm1.1Atot page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278848
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT flanked lacZ-neo cassette and loxP site were inserted upstream of exon 7 and Rox flanked hyg-pgk cassette and loxP site were inserted downstream of exon 7 via homologous recombination. Flp and Dre mediated recombination removed the selection cassettes leaving exon 7 floxed. (J:278848)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scml1 Mutation: 0 strains or lines available

References

• Original: J:278848 Papanikos F, et al., The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice. Chromosoma. 2017 Jun;126(3):399-415
• All: 1 reference(s)