Sstr5^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Sstr5^tm1Lex
• Name: somatostatin receptor 5; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:6361954
• Gene: Sstr5 Location: Chr17:25708849-25716262 bp, - strand Genetic Position: Chr17, 12.62 cM
• Alliance: Sstr5^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:249976
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin selection cassette replaced the entire coding region. (J:249976)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sstr5 Mutation: 13 strains or lines available

References

• Original: J:249976 Farb TB, et al., Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5. Endocrinology. 2017 Nov 01;158(11):3859-3873
• All: 1 reference(s)