Rps23rg1^em1Ywuz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rps23rg1^em1Ywuz
• Name: ribosomal protein S23, retrogene 1; endonuclease-mediated mutation 1, Yun-wu Zhang
• MGI ID: MGI:6361943
• Gene: Rps23rg1 Location: Chr8:3617998-3634776 bp, + strand Genetic Position: Chr8, 1.92 cM
• Alliance: Rps23rg1^em1Ywuz page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN-targeting of exon 6 deleted 5 bp deletion (ACTTC) resulting in a frameshift and premature truncation. (J:272361)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps23rg1 Mutation: 6 strains or lines available

References

• Original: J:272361 Zhao D, et al., RPS23RG1 Is Required for Synaptic Integrity and Rescues Alzheimer's Disease-Associated Cognitive Deficits. Biol Psychiatry. 2018 Aug 25
• All: 1 reference(s)