Ager^tm1.2Geno
Targeted Allele Detail

Summary

• Symbol: Ager^tm1.2Geno
• Name: advanced glycosylation end product-specific receptor; targeted mutation 1.2, Genoway
• MGI ID: MGI:6361243
• Gene: Ager Location: Chr17:34816836-34819910 bp, + strand Genetic Position: Chr17, 18.18 cM
• Alliance: Ager^tm1.2Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278881
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 4-7 were deleted via germline Cre-mediated recombination of flanking loxP sites. (J:278881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ager Mutation: 33 strains or lines available

References

• Original: J:278881 Hurtado Del Pozo C, et al., A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019 Jul 16;28(3):773-791.e7
• All: 1 reference(s)