Vgll4^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vgll4^em1Smoc
• Name: vestigial like family member 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6360735
• Synonyms: Vgll4^Vgll4-eGFP
• Gene: Vgll4 Location: Chr6:114837589-114946955 bp, - strand Genetic Position: Chr6, 53.07 cM
• Alliance: Vgll4^em1Smoc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting knocked the Vgll4-eGFP-Wpre-polyA expression cassette into the initiation exon to allow for expression under the endogenous promoter. (J:273437)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vgll4 Mutation: 24 strains or lines available

References

• Original: J:273437 Yu W, et al., VGLL4 plays a critical role in heart valve development and homeostasis. PLoS Genet. 2019 Feb;15(2):e1007977
• All: 3 reference(s)