Slc52a3^tm1.1Said
Targeted Allele Detail

Summary

• Symbol: Slc52a3^tm1.1Said
• Name: solute carrier protein family 52, member 3; targeted mutation 1.1, Hamid M Said
• MGI ID: MGI:6358739
• Synonyms: Slc52a3 LoxP⁺
• Gene: Slc52a3 Location: Chr2:151838431-151851178 bp, + strand Genetic Position: Chr2, 74.83 cM, cytoband H1
• Alliance: Slc52a3^tm1.1Said page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278571
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT and loxP flanked neomycin resistance cassette was inserted downstream, of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:278571)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc52a3 Mutation: 26 strains or lines available

References

• Original: J:278571 Subramanian VS, et al., Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption. Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15;310(4):G285-93
• All: 1 reference(s)