Card10^tm1.1Bmed
Targeted Allele Detail

Summary

• Symbol: Card10^tm1.1Bmed
• Name: caspase recruitment domain family, member 10; targeted mutation 1.1, Benjamin D Medoff
• MGI ID: MGI:6358733
• Synonyms: Card10^tm1.1Itl, CARMA3^F
• Gene: Card10 Location: Chr15:78659338-78687242 bp, - strand Genetic Position: Chr15, 37.7 cM
• Alliance: Card10^tm1.1Bmed page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278570
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 1 - 3 were flanked by loxp sites and an frt-flanked neomycin cassette. The frt-flanked neomycin cassette was removed via FLP-mediated recombination. (J:278570)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Card10 Mutation: 35 strains or lines available

References

• Original: J:278570 Causton B, et al., CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation. J Immunol. 2015 Jul 15;195(2):683-94
• All: 1 reference(s)