Coq3^tm1Hek
Targeted Allele Detail

Summary

• Symbol: Coq3^tm1Hek
• Name: coenzyme Q3 methyltransferase; targeted mutation 1, Siegfried Hekimi
• MGI ID: MGI:6358727
• Gene: Coq3 Location: Chr4:21879673-21912162 bp, + strand Genetic Position: Chr4, 9.11 cM
• Alliance: Coq3^tm1Hek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278535
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP and FRT-flanked neomycin resistance cassette replaced exons 4 and 5. (J:278535)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Coq3 Mutation: 21 strains or lines available

References

• Original: J:278535 Lapointe J, et al., The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice. J Cell Biol. 2012 Oct 15;199(2):215-24
• All: 1 reference(s)