Nintm1d(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Nintm1d(EUCOMM)Hmgu |
Name: |
ninein; targeted mutation 1d, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:6358684 |
Gene: |
Nin Location: Chr12:70058209-70160491 bp, - strand Genetic Position: Chr12, 28.94 cM, cytoband C3
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Alliance: |
Nintm1d(EUCOMM)Hmgu page
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IMPC: |
Nin gene page |
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Germline Transmission: |
Earliest citation of germline transmission:
J:277726
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: Cre-mediated excision of the Nintm1c(EUCOMM)Hmgu allele resulted in the deletion of exon 2. Immunoblotting and immunostaining analysis confirmed absence of protein in embryonic fibroblasts and skin sections, respectively. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:277726)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nin Mutation: |
82 strains or lines available
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Original: |
J:277726 Lecland N, et al., Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2) |
All: |
1 reference(s) |
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