Efr3a^tm1Bgsn
Targeted Allele Detail

Summary

• Symbol: Efr3a^tm1Bgsn
• Name: EFR3 homolog A; targeted mutation 1, Binggui Sun
• MGI ID: MGI:6358560
• Synonyms: Efr3a^f
• Gene: Efr3a Location: Chr15:65658883-65745665 bp, + strand Genetic Position: Chr15, 29.12 cM
• Alliance: Efr3a^tm1Bgsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:273433
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. (J:273433)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efr3a Mutation: 56 strains or lines available

References

• Original: J:273433 Qian Q, et al., Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway. FASEB J. 2017 May;31(5):2104-2113
• All: 3 reference(s)