Tg(GFAP-Nfe2l2)173.4Jaj
Transgene Detail

Summary

• Symbol: Tg(GFAP-Nfe2l2)173.4Jaj
• Name: transgene insertion 173.4, Jeffrey Johnson
• MGI ID: MGI:6358536
• Synonyms: hGFAP-Nrf2, Tg173.4
• Transgene: Tg(GFAP-Nfe2l2)173.4Jaj Location: unknown
• Alliance: Tg(GFAP-Nfe2l2)173.4Jaj page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(GFAP-Nfe2l2)173.4Jaj expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nfe2l2 (MGI:108420)	Human promoter

• A human GFAP promoter drives the expression of a mouse Nfe2l2 cDNA. (J:143048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:143048 Vargas MR, et al., Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J Neurosci. 2008 Dec 10;28(50):13574-81
• All: 9 reference(s)