Nbea^em1Hssh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nbea^em1Hssh
• Name: neurobeachin; endonuclease-mediated mutation 1, Hee-Sup Shin
• MGI ID: MGI:6358512
• Gene: Nbea Location: Chr3:55532616-56091122 bp, - strand Genetic Position: Chr3, 26.61 cM
• Alliance: Nbea^em1Hssh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 17-bp out-of-frame deletion in exon 22 was created using TALEN genome editing technology. This resulted in the creation of a premature stop codon in exon 22. (J:278102)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nbea Mutation: 139 strains or lines available

References

• Original: J:278102 Lee B, et al., The Possible Role of Neurobeachin in Extinction of Contextual Fear Memory. Sci Rep. 2018 Sep 13;8(1):13752
• All: 1 reference(s)