Nsmftm1.2Mrkr
Targeted Allele Detail
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Symbol: |
Nsmftm1.2Mrkr |
Name: |
NMDA receptor synaptonuclear signaling and neuronal migration factor; targeted mutation 1.2, Michael R Kreutz |
MGI ID: |
MGI:6358416 |
Gene: |
Nsmf Location: Chr2:24944370-24952893 bp, + strand Genetic Position: Chr2, 16.94 cM, cytoband A3
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Alliance: |
Nsmftm1.2Mrkr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:232404
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted into the 5UTR of exon 1, an FRT-flanked PGK-neomycin selection cassette was inserted after exon 2, followed by a loxP site and a third loxP site downstream of exon 3. Flp-mediated recombination removed the selection cassette and cre-mediated recombination deleted exons 1-3. Western blot analysis confirmed absence of protein.
(J:232404)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nsmf Mutation: |
18 strains or lines available
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Original: |
J:232404 Spilker C, et al., A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis. PLoS Genet. 2016 Mar;12(3):e1005907 |
All: |
1 reference(s) |
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