Ehmt2^tm1.2Pes
Targeted Allele Detail

Summary

• Symbol: Ehmt2^tm1.2Pes
• Name: euchromatic histone lysine N-methyltransferase 2; targeted mutation 1.2, Piroska E Szabo
• MGI ID: MGI:6358094
• Gene: Ehmt2 Location: Chr17:35117445-35133028 bp, + strand Genetic Position: Chr17, 18.45 cM
• Alliance: Ehmt2^tm1.2Pes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276738
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 26-27 were deleted via Cre-mediated recombination of flanking loxP sites. (J:276738)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ehmt2 Mutation: 57 strains or lines available

References

• Original: J:276738 Zeng TB, et al., EHMT2 and SETDB1 protect the maternal pronucleus from 5mC oxidation. Proc Natl Acad Sci U S A. 2019 May 28;116(22):10834-10841
• All: 3 reference(s)