Sirt5^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Sirt5^tm1Ics
• Name: sirtuin 5; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6358037
• Synonyms: Sirt5^fl, Sirt5^floxed
• Gene: Sirt5 Location: Chr13:43518972-43548679 bp, + strand Genetic Position: Chr13, 21.6 cM
• Alliance: Sirt5^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205149
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 4 was flanked with LoxP sites. (J:205149)

Tumor Data

List all tumor models in MMHCdb carrying Sirt5^tm1Ics

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sirt5 Mutation: 30 strains or lines available

References

• Original: J:205149 Yu J, et al., Metabolic characterization of a Sirt5 deficient mouse model. Sci Rep. 2013;3:2806
• All: 4 reference(s)