Gt(ROSA)26Sor^{tm1(ERBB4)Kles}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(ERBB4)Kles}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Klaus Elenius
• MGI ID: MGI:6357205
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(ERBB4)Kles} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180153
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(ERBB4)Kles} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ERBB4 (2066)

  Erbb4

  (MGI:104771)

  JMa CYT-2 isoform

• Mutation details: The coding region for the isoform composed of extracellular juxtamembrane domain JMa and intracellular cytoplasmic domain CYT-2 of human ERBB4 cDNA was under the control of a floxed stop cassette inserted into the locus. (J:180153)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1058 strains or lines available

References

• Original: J:180153 Veikkolainen V, et al., ErbB4 Modulates Tubular Cell Polarity and Lumen Diameter during Kidney Development. J Am Soc Nephrol. 2012 Jan;23(1):112-22
• All: 1 reference(s)