Mir31^tm1.1Bwg
Targeted Allele Detail

Summary

• Symbol: Mir31^tm1.1Bwg
• Name: microRNA 31; targeted mutation 1.1, Brigham and Women's Hospital
• MGI ID: MGI:6357180
• Synonyms: Mir31^-
• Gene: Mir31 Location: Chr4:88828794-88828899 bp, - strand Genetic Position: Chr4, 42.05 cM
• Alliance: Mir31^tm1.1Bwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259150
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A null/knockout allele was generated via Cre-mediated deletion of inserted loxP sites. Details not available. (J:259150)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir31 Mutation: 4 strains or lines available

References

• Original: J:259150 Moffett HF, et al., The microRNA miR-31 inhibits CD8(+) T cell function in chronic viral infection. Nat Immunol. 2017 Jul;18(7):791-799
• All: 1 reference(s)