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Kcns1tm1.1Kcl
Targeted Allele Detail
Summary
Symbol: Kcns1tm1.1Kcl
Name: K+ voltage-gated channel, subfamily S, 1; targeted mutation 1.1, King's College of London
MGI ID: MGI:6357176
Synonyms: Kcns1 f
Gene: Kcns1  Location: Chr2:164005539-164013033 bp, - strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Kcns1tm1.1Kcl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:276188
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette was inserted upstream of a floxed exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:276188)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Kcns1 Mutation:  29 strains or lines available
References
Original:  J:276188 Tsantoulas C, et al., Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity. Pain. 2018 Aug;159(8):1641-1651
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory