About   Help   FAQ
Targeted Allele Detail
Symbol: Kcns1tm1.1Kcl
Name: K+ voltage-gated channel, subfamily S, 1; targeted mutation 1.1, King's College of London
MGI ID: MGI:6357176
Synonyms: Kcns1 f
Gene: Kcns1  Location: Chr2:164005539-164013033 bp, - strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Kcns1tm1.1Kcl page
Germline Transmission:  Earliest citation of germline transmission: J:276188
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neomycin resistance cassette was inserted upstream of a floxed exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:276188)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Kcns1 Mutation:  29 strains or lines available
Original:  J:276188 Tsantoulas C, et al., Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity. Pain. 2018 Aug;159(8):1641-1651
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
MGI 6.24
The Jackson Laboratory