Tg(ACTB-H60a*)1Dcr
Transgene Detail

Summary

• Symbol: Tg(ACTB-H60a*)1Dcr
• Name: transgene insertion 1, Derry C Roopenian
• MGI ID: MGI:6357170
• Synonyms: H60H Tg
• Transgene: Tg(ACTB-H60a*)1Dcr Location: unknown
• Alliance: Tg(ACTB-H60a*)1Dcr page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-H60a*)1Dcr expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	H60a (MGI:1306817)	harbors an N to H substitution at position 4 of the H60a epitope sequence (LTFNYRNL)

• Mutation details: The transgene was designed with the chicken beta-actin promoter/CMV enhancer directing expression of FLAG-tagged mouse H60a cDNA modified to harbor an asparagine (N) to histidine (H) substitution at position 4 of the H60a epitope sequence (LTFNYRNL). (J:277928)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:277928 Ryu SJ, et al., A single-amino-acid variant of the H60 CD8 epitope generates specific immunity with diverse TCR recruitment. Mol Cells. 2012 Apr;33(4):393-9
• All: 1 reference(s)