Fam20b^tm1.1Xwamg
Targeted Allele Detail

Summary

• Symbol: Fam20b^tm1.1Xwamg
• Name: FAM20B, glycosaminoglycan xylosylkinase; targeted mutation 1.1, Xiaofang Wang
• MGI ID: MGI:6356832
• Synonyms: Fam20B^flox
• Gene: Fam20b Location: Chr1:156506102-156546656 bp, - strand Genetic Position: Chr1, 67.71 cM
• Alliance: Fam20b^tm1.1Xwamg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:264724
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 4 and 5 were flanked by loxP sites and an frt-flanked neomycin selection cassette. FLP-mediated recombination removed the neomycin selection cassette in the germline. (J:264724)

Expression

In Mice Carrying this Mutation:

27 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam20b Mutation: 29 strains or lines available

References

• Original: J:264724 Tian Y, et al., Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors. Eur J Oral Sci. 2015 Dec;123(6):396-402
• All: 7 reference(s)