Trim31^em3Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim31^em3Cya
• Name: tripartite motif-containing 31; endonuclease-mediated mutation 3, Cyagen Biosciences
• MGI ID: MGI:6356830
• Synonyms: KO3, Trim31^em3Cgen
• Gene: Trim31 Location: Chr17:37209022-37221109 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Trim31^em3Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN mutagenesis induced a 5 bp deletion of GGGCA at position 94-98 of the open reading frame. (J:243237)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim31 Mutation: 19 strains or lines available

References

• Original: J:243237 Song H, et al., The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. Nat Commun. 2016 Dec 08;7:13727
• All: 1 reference(s)