Nisch^tm1.2Sala
Targeted Allele Detail

Summary

• Symbol: Nisch^tm1.2Sala
• Name: nischarin; targeted mutation 1.2, Suresh K Alahari
• MGI ID: MGI:6356803
• Synonyms: Nc^deltae7-10, Nisch^tm1.2Itl
• Gene: Nisch Location: Chr14:30892885-30928783 bp, - strand Genetic Position: Chr14, 19.09 cM, cytoband B
• Alliance: Nisch^tm1.2Sala page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:245894
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 7-10 were deleted via Cre-mediated recombination of flanking loxP sites in the germline. (J:245894)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nisch Mutation: 72 strains or lines available

References

• Original: J:245894 Dong S, et al., Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase. J Biol Chem. 2017 Oct 13;292(41):16833-16846
• All: 1 reference(s)