Kirrel1^tm1.2Geno
Targeted Allele Detail

Summary

• Symbol: Kirrel1^tm1.2Geno
• Name: kirre like nephrin family adhesion molecule 1; targeted mutation 1.2, Genoway
• MGI ID: MGI:6356795
• Synonyms: Neph1 KO
• Gene: Kirrel1 Location: Chr3:86985900-87082054 bp, - strand Genetic Position: Chr3, 38.18 cM, cytoband F1
• Alliance: Kirrel1^tm1.2Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 12-15 were deleted via Cre-mediated recombination of flanking loxP sites in the germline. (J:241326)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kirrel1 Mutation: 194 strains or lines available

References

• Original: J:241326 Grahammer F, et al., A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016 Jun 16;1(9)
• All: 2 reference(s)