Abca4^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Abca4^tm1Itl
• Name: ATP-binding cassette, sub-family A member 4; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:6356786
• Gene: Abca4 Location: Chr3:121838092-121973772 bp, + strand Genetic Position: Chr3, 52.94 cM
• Alliance: Abca4^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278265
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 of the gene was replaced with a Neomycin selection cassette. (J:278265)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abca4 Mutation: 113 strains or lines available

References

• Original: J:278265 Bavik C, et al., Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity. PLoS One. 2015;10(5):e0124940
• All: 1 reference(s)