Zbp1^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Zbp1^tm1Tac
• Name: Z-DNA binding protein 1; targeted mutation 1, Taconic
• MGI ID: MGI:6356680
• Gene: Zbp1 Location: Chr2:173048405-173060715 bp, - strand Genetic Position: Chr2, 95.83 cM, cytoband H3
• Alliance: Zbp1^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242990
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• The 5' UTR and exon 1 corresponding to NCBI37/mm9 chr2:173,043,537-173,045,687 was deleted. (J:242990)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbp1 Mutation: 29 strains or lines available

References

• Original: J:242990 Newton K, et al., RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016 Dec 01;540(7631):129-133
• All: 2 reference(s)