Atp2b1^tm1.2Hiraw
Targeted Allele Detail

Summary

• Symbol: Atp2b1^tm1.2Hiraw
• Name: ATPase, Ca++ transporting, plasma membrane 1; targeted mutation 1.2, Nobuhito Hirawa
• MGI ID: MGI:6356331
• Synonyms: Atp2b1^-
• Gene: Atp2b1 Location: Chr10:98750268-98862005 bp, + strand Genetic Position: Chr10, 50.97 cM, cytoband C3
• Alliance: Atp2b1^tm1.2Hiraw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271691
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 10 was deleted in the germline via Cre-mediated recombination of flanking loxP sites. (J:271691)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp2b1 Mutation: 64 strains or lines available

References

• Original: J:271691 Fujiwara A, et al., Impaired nitric oxide production and increased blood pressure in systemic heterozygous ATP2B1 null mice. J Hypertens. 2014 Jul;32(7):1415-23; discussion 1423
• All: 2 reference(s)