Ffar1^tm1Kaem
Targeted Allele Detail

Summary

• Symbol: Ffar1^tm1Kaem
• Name: free fatty acid receptor 1; targeted mutation 1, Kae Matsuda-Nagasumi
• MGI ID: MGI:6355957
• Synonyms: GPR40/FFAR1 KO
• Gene: Ffar1 Location: Chr7:30559993-30560895 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar1^tm1Kaem page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275372
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A segment of the gene was replaced with a neomycin selection cassette. (J:275372)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar1 Mutation: 18 strains or lines available

References

• Original: J:275372 Matsuda-Nagasumi K, et al., Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition. Diabetes Obes Metab. 2013 Jun;15(6):538-45
• All: 4 reference(s)