Parpbp^tm1.1Chum
Targeted Allele Detail

Summary

• Symbol: Parpbp^tm1.1Chum
• Name: PARP1 binding protein; targeted mutation 1.1, Shinichiro Chuma
• MGI ID: MGI:6343509
• Synonyms: Pari^-
• Gene: Parpbp Location: Chr10:87927294-87982803 bp, - strand Genetic Position: Chr10, 43.7 cM, cytoband C2
• Alliance: Parpbp^tm1.1Chum page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:248791
• Parent Cell Line: KY1.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 5 and 6 are deleted after Cre-mediated recombination of flanking loxP sites in the germline. (J:248791)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Parpbp Mutation: 35 strains or lines available

References

• Original: J:248791 Mochizuki AL, et al., PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice. Mol Cell Biol. 2017 Dec 1;37(23)
• All: 1 reference(s)