Lvrn^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lvrn^em1Osb
• Name: laeverin; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6343490
• Gene: Lvrn Location: Chr18:46983105-47040309 bp, + strand Genetic Position: Chr18, 24.84 cM, cytoband C
• Alliance: Lvrn^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The molecular lesion is a 62 bp deletion in the coding sequence. PCR and immunoblot analysis demonstrated the absence of transcript and encoded protein, respectively. (J:277364)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lvrn Mutation: 51 strains or lines available

References

• Original: J:277364 Tobita T, et al., Lvrn expression is not critical for mouse placentation. J Reprod Dev. 2019 Jun 14;65(3):239-244
• All: 1 reference(s)