Izumo1r^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Izumo1r^em1Osb
• Name: IZUMO1 receptor, JUNO; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6343374
• Synonyms: Juno^em1Osb
• Gene: Izumo1r Location: Chr9:14797110-14815245 bp, - strand Genetic Position: Chr9, 4.42 cM
• Alliance: Izumo1r^em1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240828
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mutagenesis induced a 10bp deletion in the gene. (J:240828)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Izumo1r Mutation: 23 strains or lines available

References

• Original: J:240828 Kato K, et al., Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization. Nat Commun. 2016 Jul 15;7:12198
• All: 1 reference(s)