Cldn3^tm1Mfur
Targeted Allele Detail

Summary

• Symbol: Cldn3^tm1Mfur
• Name: claudin 3; targeted mutation 1, Mikio Furuse
• MGI ID: MGI:6342909
• Gene: Cldn3 Location: Chr5:135015068-135016326 bp, + strand Genetic Position: Chr5, 74.93 cM
• Alliance: Cldn3^tm1Mfur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275432
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced all but the last 30 nubleotides of the open reading frame. (J:275432)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cldn3 Mutation: 12 strains or lines available

References

• Original: J:275432 Castro Dias M, et al., Claudin-3-deficient C57BL/6J mice display intact brain barriers. Sci Rep. 2019 Jan 18;9(1):203
• All: 2 reference(s)