Kdg4^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kdg4^em1(IMPC)Bay
• Name: alpha-ketoglutarate dehydrogenase subunit 4; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6342898
• Gene: Kdg4 Location: Chr13:100872463-100881167 bp, - strand Genetic Position: Chr13, 53.23 cM, cytoband D1
• Alliance: Kdg4^em1(IMPC)Bay page
• IMPC: Kdg4 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences AAGATTGTGCAGAGTGCTGG, ACTGAAGGTGTTTAGTTATG, GATCCCATTTGACAAAACAA, and TAAAATAAACTACTACTCAG that targeted exon(s) ENSMUSE00001207138.2 ENSMUSE00001255891.2 ENSMUSE00001302412.2 ENSMUSE00001620581.1 ENSMUSE00001620582.1. This resulted in deletion(s) of 2397 bp (location: Chr13:100875446-100877842; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kdg4 Mutation: 9 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)