Synm^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Synm^tm1Ics
• Name: synemin, intermediate filament protein; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6342884
• Gene: Synm Location: Chr7:67379909-67409490 bp, - strand Genetic Position: Chr7, 37.12 cM
• Alliance: Synm^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268425
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Homologous recombination introduced loxP sequences into the promoter and intron 1. (J:268425)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Synm Mutation: 56 strains or lines available

References

• Original: J:268425 Li Z, et al., Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy. J Cell Sci. 2014 Nov 1;127(Pt 21):4589-601
• All: 1 reference(s)