Tg(CAG-Map3k13/tdTomato)1Bzh
Transgene Detail

Summary

• Symbol: Tg(CAG-Map3k13/tdTomato)1Bzh
• Name: transgene insertion 1, Binhai Zheng
• MGI ID: MGI:6342447
• Synonyms: LZK^OE
• Transgene: Tg(CAG-Map3k13/tdTomato)1Bzh Location: unknown
• Alliance: Tg(CAG-Map3k13/tdTomato)1Bzh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Map3k13/tdTomato)1Bzh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Map3k13 (MGI:2444243)

• Mutation details: The transgene construct carries two loxP sites flanking a STOP cassette upstream of an LZK-T2A-tdTomato (tdT) fusion gene, uinder the control of a chicken actin promoter. Cre-mediated excision of STOP activates LZK-T2A-tdT, leading to overexpression of LZK and the associated fluorescent reporter tdTomato. (J:260350)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:260350 Chen M, et al., Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS. Cell Rep. 2018 Mar 27;22(13):3587-3597
• All: 2 reference(s)