Ndufa13^tm1.1Dkalv
Targeted Allele Detail

Summary

• Symbol: Ndufa13^tm1.1Dkalv
• Name: NADH:ubiquinone oxidoreductase subunit A13; targeted mutation 1.1,Dhan Kalvakolanu
• MGI ID: MGI:6341998
• Synonyms: Grim-19^f
• Gene: Ndufa13 Location: Chr8:70346830-70355208 bp, - strand Genetic Position: Chr8, 34.03 cM, cytoband C1
• Alliance: Ndufa13^tm1.1Dkalv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202910
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert an FRT-flanked neomycin selection cassette followed by a loxP site upstream of exon 3, and a second loxP site downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 3 floxed. (J:202910)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ndufa13 Mutation: 14 strains or lines available

References

• Original: J:202910 Kalakonda S, et al., Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):E4213-22
• All: 2 reference(s)