Idh3a^{em1(IMPC)Kmpc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Idh3a^{em1(IMPC)Kmpc}
• Name: isocitrate dehydrogenase 3 (NAD+) alpha; endonuclease-mediated mutation 1, Korea Mouse Phenotyping Center
• MGI ID: MGI:6336121
• Gene: Idh3a Location: Chr9:54493795-54511946 bp, + strand Genetic Position: Chr9, 29.7 cM
• Alliance: Idh3a^{em1(IMPC)Kmpc} page
• IMPC: Idh3a gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Korea Mouse Phenotype Consortium using Cas9 and guides with spacer sequences CTAGGCACCTATTCAGTGGG, GATGGGCTTGAAAGGTACAG, GCTTCTAGGCACCTATTCAG, and TGGGCTTGAAAGGTACAGTG that targeted exon(s) ENSMUSE00000993125.2. This resulted in deletion(s) of 110 bp (location: Chr9:54502459-54502568; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Idh3a Mutation: 22 strains or lines available

References

• Original: J:237616 MGI and IMPC, MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). MGI Direct Data Submission. 2017-8
• All: 4 reference(s)