Tg(SFTPC-TK*)1Dris
Transgene Detail

Summary

• Symbol: Tg(SFTPC-TK*)1Dris
• Name: transgene insertion 1, Barbara Driscoll
• MGI ID: MGI:6331067
• Synonyms: SPCTK
• Transgene: Tg(SFTPC-TK*)1Dris Location: unknown
• Alliance: Tg(SFTPC-TK*)1Dris page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains (from 5' to 3') an ampicillin resistance cassette, a replication origin, a minimal human cytomegalovirus promoter/enhancer sequence, some HIV-1 lentiviral sequences (R region, truncated 5' LTR [U5], psi [packaging signal], reverse response element, central polypurine tract and central termination sequence, a 3.7 kbp human surfactant associated protein C promoter sequence, a Herpes simplex thymidine kinase 1 mutant SR39TK sequence and additional HIV-1 lentiviral sequences (3' LTR, R region, truncated 5' LTR [U5]). (J:277115)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:277115 Garcia O, et al., Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair. Am J Respir Cell Mol Biol. 2016 Mar;54(3):319-30
• All: 1 reference(s)