Msi1^tm2.1Geno
Targeted Allele Detail

Summary

• Symbol: Msi1^tm2.1Geno
• Name: musashi RNA-binding protein 1; targeted mutation 2.1, Genoway
• MGI ID: MGI:6324498
• Synonyms: Msi1^f, Msi1^flox
• Gene: Msi1 Location: Chr5:115567734-115593757 bp, + strand Genetic Position: Chr5, 56.09 cM, cytoband E3-F
• Alliance: Msi1^tm2.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235743
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 1 and an FRT-flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 4. Cre-mediated recombination removed the floxed neo cassette. (J:235743)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msi1 Mutation: 29 strains or lines available

References

• Original: J:235743 Fox RG, et al., Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature. 2016 Jun 16;534(7607):407-11
• All: 1 reference(s)