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Endonuclease-mediated Allele Detail
Symbol: Slc36a1em1(IMPC)Tcp
Name: solute carrier family 36 (proton/amino acid symporter), member 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI ID: MGI:6324175
Gene: Slc36a1  Location: Chr11:55095176-55127156 bp, + strand  Genetic Position: Chr11, 32.33 cM
Alliance: Slc36a1em1(IMPC)Tcp page
IMPC: Slc36a1 gene page
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele from project TCPR1331 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ATTGTTTTGAGACGAGACTT and ATCACCATGCCGGTCCCAAT targeting the 5' side and ACTGGGCGAGCAGGTTACGT and TCGCCCTCAAGATTACTTCC targeting the 3' side of a critical region. This resulted in a 521-bp del Chr11:55218714-55219234; 23-bp del Chr11:55219287-55219309_insGAG (GRCm38). (J:265051)
Inheritance:    Not Specified
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slc36a1 Mutation:  22 strains or lines available
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory